1、科研奖励:河北省自然科学一等奖
河北省自然科学一等奖,2022ZR1003,血管平滑肌细胞表型调节因子的新发现及其意义
2、科研奖励:河北省科技进步二等奖
河北省科技进步二等奖,2022JB2056,围术期老龄认知障碍与钙离子相关发病机制研究及临床防治策略
3、科研奖励:河北省科技进步二等奖
河北省科学技术进步奖二等奖,2019JB2039,气体分子硫化氢在高血压发病机制中的研究及临床应用
4、科研奖励:河北省自然科学三等奖
河北省自然科学奖三等奖,2021ZR3009,内质网应激在血管钙化及其心脏并发症中作用及其调控机制研究
5、代表性论著:中科院1区论文
Li J, Yao Z, Liu X, Duan R, Yi X, Ayoub A, Sanders JO, Mesfin A, Xing L, Boyce BF. TGFβ1+CCR5+ neutrophil subset increases in bone marrow and causes age-related osteoporosis in male mice. Nat Commun. 2023 Jan 11;14(1):159. (中科院1区,IF:17.694)
6、代表性论著:中科院1区论文
Gao J, Chen Y, Wang H, Li X, Li K, Xu Y, Xie X, Guo Y, Yang N, Zhang X, Ma D, Lu HS, Shen YH, Liu Y, Zhang J, Chen YE, Daugherty A, Wang DW, Zheng L. Gasdermin D Deficiency in Vascular Smooth Muscle Cells Ameliorates Abdominal Aortic Aneurysm Through Reducing Putrescine Synthesis. Adv Sci (Weinh). 2023 Feb;10(5):e2204038. (中科院1区,IF:15.1)
7、代表性论著:中科院1区论文
Xu F, Wang X, Li Y, Gao F, Yin C, Yu J, Li W, Zhu L, Wang Q. Combined femoral artery block and femoral nerve block reduces thigh tourniquet-induced hypertension. J Clin Anesth. 2023 May;85:111039.
8、代表性论著:中科院1区论文
Zhou C, Lin Z, Cao H, Chen Y, Li J, Zhuang X, Ma D, Ji L, Li W, Xu S, Pan B, Zheng L. Anxa1 in smooth muscle cells protects against acute aortic dissection. Cardiovasc Res. 2022 May 6;118(6):1564-1582. (中科院1区,IF:10.8)
9、代表性论著:中科院1区论文
Zhang M, Gao J, Zhao X, Zhao M, Ma D, Zhang X, Tian D, Pan B, Yan X, Wu J, Meng X, Yin H, Zheng L. p38α in macrophages aggravates arterial endothelium injury by releasing IL-6 through phosphorylating megakaryocytic leukemia 1. Redox Biol. 2021-01-01; 38 101775. (中科院1区,IF:11.4)
10、代表性论著:中科院1区论文
Ma D, Zheng B, Liu HL, Zhao YB, Liu X, Zhang XH, Li Q, Shi WB, Suzuki T, Wen JK. Klf5 down-regulation induces vascular senescence through eIF5a depletion and mitochondrial fission. PLOS BIOL. 2020-08-01; 18 (8): e3000808. (中科院1区,IF:9.8)
11、代表性论著:中科院1区论文
Li J, Yi X, Yao Z, Chakkalakal JV, Xing L, Boyce BF. TNF Receptor-Associated Factor 6 Mediates TNFα-Induced Skeletal Muscle Atrophy in Mice During Aging. J Bone Miner Res. 2020 Aug;35(8):1535-1548. (中科院1区,IF:6.741)
12、代表性论著:中科院2区论文
Du J, Wang P, Gou Q, Jin S, Xue H, Li D, Tian D, Sun J, Zhang X, Teng X, Wu Y. Hydrogen sulfide ameliorated preeclampsia via suppression of toll-like receptor 4-activated inflammation in the rostral ventrolateral medulla of rats. Biomed Pharmacother. 2022 Apr 25;150:113018. (中科院2区top,IF:7.5)
13、代表性论著:中科院2区论文
Zhang Y, Zhang H, Yang Z, Zhang XH, Miao Q, Li M, Zhai TY, Zheng B, Wen JK. miR-155 down-regulation protects the heart from hypoxic damage by activating fructose metabolism in cardiac fibroblasts. J Adv Res. 2022 Jul;39:103-117.(中科院2区,IF:10.4)
14、代表性论著:中科院2区论文
Li J, Li X, Sun W, Zhang J, Yan Q, Wu J, Jin J, Lu R, Miao D. Specific overexpression of SIRT1 in mesenchymal stem cells rescues hematopoiesis niche in BMI1 knockout mice through promoting CXCL12 expression. Int J Biol Sci. 2022 Feb 28;18(5):2091-2103. (中科院2区,IF:9.2)
15、代表性论著:中科院2区论文
Zhang Q, Li Y, Yu J, Yin C, Guo J, Zhao J, Wang Q. TLR3 deletion inhibits programmed necrosis of brain cells in neonatal mice with sevoflurane-induced cognitive dysfunction. Aging (Albany NY). 2022 Jun 6;14(11):4714-4727. (中科院2区,IF:5.2)
16、代表性论著:中科院2区论文
Li Y, Zhang Q, Yan W, Wang X, Yu J, Yin C, Zhou Q, Hou Z, Wang Q. Young plasma reverses anesthesia and surgery-induced cognitive impairment in aged rats by modulating hippocampal synaptic plasticity. Front Aging Neurosci. 2022 Sep 6;14:996223. (中科院2区,IF:4.8)
17、代表性论著:中科院2区论文
Wang X, Li Y, Zhao J, Yu J, Zhang Q, Xu F, Zhang Y, Zhou Q, Yin C, Hou Z, Wang Q. Activation of astrocyte Gq pathway in hippocampal CA1 region attenuates anesthesia/surgery induced cognitive dysfunction in aged mice. Front Aging Neurosci. 2022 Nov 11;14:1040569. (中科院2区,IF:4.8)
18、代表性论著:中科院2区论文
Zhang Q, Li Y, Wang X, Yin C, Zhou Q, Guo J, Zhao J, Xian X, Hou Z, Wang Q. Sevoflurane exposure causes neuronal apoptosis and cognitive dysfunction by inducing ER stress via activation of the inositol 1, 4, 5-trisphosphate receptor. Front Aging Neurosci. 2022 Oct 20;14:990679. (中科院2区,IF:4.8)
19、代表性论著:中科院2区论文
Zhang Q, Li Y, Yin C, Gao M, Yu J, Guo J, Xian X, Hou Z, Wang Q. IL-17A deletion reduces sevoflurane-induced neurocognitive impairment in neonatal mice by inhibiting NF-κB signaling pathway. Bioengineered. 2022 Jun;13(6):14562-14577. (中科院2区,IF:4.9)
20、代表性论著:中科院2区论文
Chen YH, Teng X, Hu ZJ, Tian DY, Jin S, Wu YM. Hydrogen Sulfide Attenuated Sepsis-Induced Myocardial Dysfunction Through TLR4 Pathway and Endoplasmic Reticulum Stress. Front Physiol. 2021 Jun 9;12:653601. (中科院2区top,IF:4.755)
21、代表性论著:中科院2区论文
Li Y, Li Y, Li Y, Yang Z, Geng H, Liu C, Hao W, Yang R, Jin S, Wu Y, Wang X, Teng X. Inhibition of endoplasmic reticulum stress mediates the ameliorative effect of apelin on vascular calcification. J Mol Cell Cardiol. 2021 Mar;152:17-28. (中科院2区,IF:5.763)
22、代表性论著:中科院2区论文
Tian D, Teng X, Jin S, Chen Y, Xue H, Xiao L, Wu Y. Endogenous hydrogen sulfide improves vascular remodeling through PPARδ/SOCS3 signaling. J Adv Res. 2020 Jun 20; 27: 115-125. (中科院2区,IF:10.4)
23、代表性论著:中科院2区论文
Cao YK, Guo Q, Ma HJ, Wang R, Teng X, Wu Y. Microinjection of urotensin II into the rostral ventrolateral medulla increases sympathetic vasomotor tone via the GPR14/ERK pathway in rats. Hypertens Res. 2020 Aug;43(8):765-771. (中科院2区,IF:5.4)
24、代表性论著:中科院2区论文
Feng X, Guo Q, Xue H, Duan X, Jin S, Wu Y. Hydrogen Sulfide Attenuated Angiotensin II-Induced Sympathetic Excitation in Offspring of Renovascular Hypertensive Rats. Front Pharmacol. 2020 Sep 11;11:565726. (中科院2区,IF:5.811)
25、代表性论著:中科院2区论文
Jin S, Dai J, Teng X, Wu YM. Adverse effects of sympathetic activation should not be neglected during the coronavirus disease 2019 pandemic. Chin Med J (Engl). 2020 Sep 14;134(4):413-414. (中科院2区,IF:6.1)
26、代表性论著:中文核心
李艳青, 黄盼娜, 张淏喆, 韩蕗羽, 苗若湘, 冯莞芸, 潘华, 冯林, 吴新华, 何娟, 滕旭, 王晓宁.慢性心理应激通过糖皮质激素促进主动脉中膜钙化. 生理学报, 2022; 74(06): 927-938.(中文核心)
27、代表性论著:中文核心
于家旭,张琦,尹春平,李亚南,李伟,朱炼,侯志勇,王秋筠. NMDA受体在七氟烷麻醉致老龄小鼠海马神经元程序性坏死中的作用. 中华麻醉学杂志, 2022, 42(1): 55-59. (中文核心)
28、代表性论著:中文核心
张琦,李亚南,尹春平,张亚辉,朱炼,侯志勇,王秋筠. 七氟烷对大鼠离体海马神经元程序性坏死的影响:与兰尼碱受体的关系. 中华麻醉学杂志, 2021, 41(1): 52-55. (中文核心)
29、专利授权:发明专利
Sal-miR-58及其在抑制血管炎性反应和动脉瘤形成中的用途,CN110511930B,发明专利,授权,2023.01.10
30、专利授权:实用新型专利
一种可加湿灭菌的麻醉剂过滤器,实用新型专利,CN215135230U,授权,2021.12.14
31、专利授权:实用新型专利
一种输液管的加热监测装置,实用新型专利,CN215083531U,授权,2021.12.10
32、专利申请:发明专利
一种盆腔脏器脱垂模型,ZL202210288971.5,发明专利,申报